Consequences and Utility of the Zinc-Dependent Metalloprotease Activity of Anthrax Lethal Toxin
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چکیده
منابع مشابه
Consequences and Utility of the Zinc-Dependent Metalloprotease Activity of Anthrax Lethal Toxin
Anthrax is caused by the gram-positive bacterium Bacillus anthracis. The pathogenesis of this disease is dependent on the presence of two binary toxins, edema toxin (EdTx) and lethal toxin (LeTx). LeTx, the major virulence factor contributing to anthrax, contains the effector moiety lethal factor (LF), a zinc-dependent metalloprotease specific for targeting mitogen-activated protein kinase kina...
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ژورنال
عنوان ژورنال: Toxins
سال: 2010
ISSN: 2072-6651
DOI: 10.3390/toxins2051038